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Further research is ongoing to determine its long-term safety and efficacy for obesity treatment
NICE guidelines recommend evidence-based weight management through dietary modification (600 kcal/day deficit), 150300 minutes weekly moderate-intensity physical activity, and behavioural change strategies
It is important to understand both common and rare adverse reactions before beginning treatment
NICE obesity guidance recommends evidence-based interventions including dietary change, physical activity, and licensed medications such as orlistat or semaglutide
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