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Adding extra targets has shown diminishing returns and often worse tolerability
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Grams 2 Key Points Compared with glucagon-like peptide-1 receptor agonists, sodium-glucose cotransporter 2 (SGLT2) inhibitors were associated with a lower risk of kidney failure among individuals with type 2 diabetes
CrossRef Quercetin enhances muscle FNDC5/irisin, partly through AMPK activation, and induces white adipose tissue browning in high-fat-fed rats Victoria Muscia Saez, Diahann Jeanette Perdicaro, Cecilia Rodriguez Lanzi, Eleonora Cremonini, Patricia Oteiza, Marcela Alejandra Vazquez Prieto Archives of Biochemistry and Biophysics.2026
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