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N Engl J Med (2017) 377:206372
This is a necessary step in directing the metabolism towards jasmonic acid, as this compound only (after conversion to its CoA ester) can undergo three cycles of oxidation catalysed by the multifunctional enzyme complex acyl-CoA oxidase to give the 12carbon 7 iso jasmonic acid
Among nine APX genes identified in Arabidopsis , three were found to be encoded in cytosol whereas the other six were distributed in stroma, thylakoid, and peroxisome (Chew et al., 2003
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