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CT-388 is also being investigated in an additional phase II study (CT388-104) to evaluate CT-388 in obesity or those with excess weight and have type 2 diabetes

Next, scaffolding analysis was carried out and it was found that R1 of compound 3f was substituted with 3-OCH3 and 4-OH on the A ring, and R1 of compounds 3m and 3n was substituted with 3-OCH3 and 4-OH on both the A and B rings