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Typically, effects like increased energy, better mood, or improved metabolism can last from a few days up to two weeks, depending on the nutrient, dosage, and your bodys metabolism
A systematic review of 76 different clinical trials looking at the risk of gallbladder disease for people taking GLP-1 agonists showed that there was an increase in risk for the development of gallbladder disease when taken at higher doses for long periods of time
Finlay et al., 2020)
Another study showed that pregnant womens exposure to extremely high doses of vitamin B12 could lead to the risk of autism spectrum disorder in an unborn child
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