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It is an injectable medicine that is a combination of two hormones: glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP)
The CHMP adopted an extension to an existing indication as follows: Type 2 diabetes mellitus Mounjaro is indicated for the treatment of adults, adolescents and children aged 10 years and above with insufficiently controlled type 2 diabetes mellitus as an adjunct to diet and exercise as monotherapy when metformin is considered inappropriate due to intolerance or contraindications in addition to other medications for the treatment of diabetes
This is likely due to its triple-action mechanism, which simultaneously targets appetite, insulin sensitivity, and energy expenditure
For instance, peptide hydrolysates from soy ( Glycine max ), chickpea ( Cicer arietinum ), common bean ( Phaseolus vulgaris ), quinoa ( Chenopodium quinoa ), and amaranth ( Amaranthus hypochondriacus ) have demonstrated significant in vitro and in vivo antidiabetic activities
