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A powerful and safer alternative to insulin achieved robust glucose control for diabetes with no increased risk of hypoglycaemia or weight gain, conclude the authors of a systematic review of therapies published in The Lancet [1]
Conclusions and future directions In conclusion, the current clinical literature suggests that metabolic factors, such as BMI, diet and exercise, and metabolic disorders, such as T2DM and dyslipidemia, have a disease-modifying effect in ALS and potentially in FTLD (Table 1)
Canonical GPX4/glutathione (GSH) defense axis The canonical axis defending against ferroptosis is centered on the GPX4/GSH system (26)
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