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Activating both at the same time produces a substantially larger pulse more than the sum of the two individual effects

"Ipamorelin induces pulsatile GH release with minimal off-target effects, providing an effective means of enhancing recovery, tissue repair, and overall anabolic environment with a favorable safety profile." Kraemer et al., Sports Medicine Clinical Evidence Ipamorelin has been shown to elevate GH and IGF-1 levels without causing significant increases in cortisol or prolactin, making it an attractive choice for athletes focused on recovery

This provides an important tool for research into aging-related neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease, and offers experimental evidence for intervention strategies in neuronal aging

Int J Biochem Cell Biol 34:348357