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E1 is a thiamin pyrophosphate (TPP)-dependent -ketoacid dehydrogenase, R -lipoic acid functions as a prosthetic group essential for E2 transacetylase activity, and E3 is a flavin adenine dinucleotide (FAD)-dependent dihydrolipoamide dehydrogenase ( Figure 4 )

Although there is an increasing number of studies evaluating the effects of RPM supplementation during distinct stages of an animals life, mainly in dairy cows, a limited number of studies have adressed these effects in beef cattle, particularly regarding muscle development and beef quality

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Diabetes 61 , 29932997 (2012)