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As an investigational drug, dosing protocols are strictly controlled within clinical settings and should not be replicated outside of supervised trials
Research-grade semaglutide is supplied as a lyophilized (freeze-dried) powder and must be reconstituted with bacteriostatic water (BAC water) before use
Both medicines are recommended for use within specialist weight management services (Tier 3 or Tier 4), and eligibility criteria apply including BMI thresholds and the presence of weight-related comorbidities
It is not legally marketed as a medicine in the United States, and regulatory agencies in several countries have issued public warnings specifically against its use
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