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Preclinical studies in diet-induced obesity rodent models are ongoing to evaluate its efficacy, safety, and tolerability as a potential therapy for type 2 diabetes and obesity

GLP-1 secretion is increased by inflammatory stimuli in an IL-6-dependent manner, leading to hyperinsulinemia and blood glucose lowering

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In fact, recent clinical trials have shown that people with type 2 diabetes who have taken a dual agonist had the following markers improve significantly: body weight fasting and after-eating glucose levels insulin sensitivity total cholesterol The only GLP-1/GIP dual agonist currently on the market is tirzepatide, branded under Mounjaro