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Individual results vary, and some patients may lose less or more than the averages reported in clinical research

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Additionally, in the trial examining alcohol use disorder, a significant reduction in alcohol consumption was observed only in a specific subgroup of patients with obesity, suggesting that patient characteristics, such as BMI, might influence treatment outcomes

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( E ) Mean GSH levels in A549shNRF2-BIND-luc, -BIND-WT NRF2, -BIND-Neh4/5mut cells treated with water (control) or 2.5 ng/mL dox for 48 h

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Ethics statement The studies involving humans were approved by the University of Helsinki, Faculty of Medicine

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