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Our evidence review of peptide safety and clinical applications for weight loss covers this candidacy question in more depth
However, without appropriate nutritional guidance and support from healthcare professionals, there is a real risk that reduced food intake could compromise dietary quality, meaning people may not get enough protein, fibre, vitamins, and minerals essential for maintaining overall health. Access to Treatment and Gaps in Care Guidance from the National Institute for Health and Care Excellence (NICE) recommends semaglutide as a weight management option for people who meet specific criteria, including a body mass index (BMI) of at least 35.0 kg/m2 and comorbidity (that is, they also have other conditions such as type 2 diabetes, cardiovascular disease, etc)
Reduce visceral fat: Clinical trials show significant reductions in waist circumference and total body fat [13, 1]
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