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Importantly, diselenide linkages are dual-responsive, as they are susceptible not only to GSH reduction but also to oxidation by reactive oxygen species (ROS), such as hydrogen peroxide [59]
Supplementary Table 3 (download XLSX Whole-cell proteomic analysis of Jurkat cells in response to mitochondrial GSH depletion
Weighted gene co-expression network analysis (WGCNA) identified genotype-driven, rather than treatment-driven, gene modules, highlighting distinct transcriptional architectures between WT and KO animals
It is synthesized in the liver from three amino acids - glutamic acid, glycine and cysteine - and is used by every single cell in the body
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