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Projections have been mapped between the VTA and LSc (51), and acute stimulation of GLP-1Rs in the LSc leads to enhanced LSc dopamine transporter surface expression and function
Some real-world cohorts and pooled analyses report greater weight loss among women treated with GLP-1 RAs than among men, though findings are not entirely consistent, and effect sizes vary by agent and population studied (Rivera et al., 2024
AMPA, -amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor
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