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Six Phase I/II clinical trials enrolling approximately 900 participants confirmed an excellent safety profile with no serious adverse events attributed to the compound

In rodent knockout models where beta-3 adrenergic receptors were removed, the lipolytic response to AOD 9604 was eliminated, confirming the receptor-specific mechanism

AOD 9604 (Anti-Obesity Drug 9604) is the commercial development name given to the HGH fragment spanning amino acids 176 through 191, with a tyrosine substitution at the N-terminus replacing the native phenylalanine for stability

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