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Currently, GLP-1R agonists are mainly targeted on the endogenous GLP-1R signaling system, which causes GLP-1R agonists to have many pharmacodynamic characteristics like GLP-1
Inadequate intake of these nutrients can impair ALP production and activity
What a targeted study would look like A randomized human clinical trial comparing placebo to CLA alone, L-carnitine alone, and the combination over six to 12 months with body composition by DXA, fasting metabolic markers, kidney function and TMAO measurement would be ideal
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