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The clinical success of dual and triple incretin agonists has validated the concept that engaging multiple complementary pathways within a single molecular framework can yield superior efficacy without proportionally increasing toxicity ( 3.3 Improved tools for mechanistic validation and risk de-risking Technological advances have also improved the ability to de-risk peptide systems earlier in development
& Pryor, J
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75 The 1.4 kb increase in the patients telomere length may have resulted from the combination of Epitalon and UCT-MSC-EXs, potentially improving his mitochondrial function and biological age
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