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3 Necroptosis 3.1 Necroptotic signaling pathway Necroptosis is a highly regulated, lytic form of RCD characterized by swelling of organelle and cellular, rupture of dying cells, and the subsequent release of intracellular contents and cytokines (132)
The fetal liver exhibited higher mitochondrial activity and increased mitochondrial DNA copy numbersboth indicative of enhanced energy metabolismwithout major shifts in gene expression, suggesting that regulation may occur at the protein level (Safain et al., 2025)
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