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Broader Cancer Outcomes and Mechanistic Insights For most other cancers, recent clinical evidence demonstrates largely positive outcomes, with several meta-analyses showing no excess risk and even a reduced risk for hepatocellular carcinoma and colorectal cancer (relative to insulin users)
Schlatter P, Beglinger C, Drewe J, Gutmann H (2007) Glucagon-like peptide 1 receptor expression in primary porcine proximal tubular cells
Clinical data from semaglutide discontinuation studies shows this clearly: most participants regained a substantial portion of their lost weight within the first year after stopping
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