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Gallbladder disease : Semaglutide may increase the risk of cholelithiasis and cholecystitis

More than 20 years ago, our laboratory discovered in either genetically or diet-induced obesity rodents that treating them with a diet enriched with prebiotics such as inulin or oligofructose (i.e., inulin-type fructans) modulates the gut microbes and improves metabolic parameters together with decreasing food intake ( Later, we discovered that these effects were accompanied by an increased number of EECs L-cells ( Short chain fatty acids Approximatively 100150 mmol/kg of SCFAs can be found in the caecum and colon

First published April 2025

1) during chronic infections [54, 262, 263]