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By shrinking visceral fat stores, GLP-1s help decrease the release of inflammatory cytokines, which contributes to improved blood sugar control, lower blood pressure, and a healthier lipid profile
The preliminary cardiovascular safety data for DPP-4 inhibitors are promising, and, if the results of long-term cardiovascular studies demonstrate reductions in hard cardiovascular end points, then this may consolidate the position of the DPP-4 inhibitors as the second-line choice for combination with metformin
Its mechanism involves upregulation of growth factor expression in tendons and ligaments, promotion of collagen synthesis, and acceleration of the fibroblast recruitment that rebuilds connective tissue architecture
Edited and updated on April 11, 2022.
