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ARA-290 (cibinetide) is the most advanced, with Phase 2 data on diabetic neuropathy (NERVARA trial)

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In june of 2022, the FDA approved semaglutide for weight loss

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Hydration status may influence skin turgor and appearance, with the National Academies of Sciences, Engineering, and Medicine recommending approximately 3.7 liters total water daily for men and 2.7 liters for women (from all sources, including food)

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