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Based on how the mirror response of peripheral-to-central nervous system immune signaling works, this is the general pattern one would expect based on a paper from our group, which hypothesizes that some cases of ME/CFS could be explained by exaggerated afferent neuroimmune signaling entering the central nervous system at the nucleus of the solitary tract (NTS) in dorsal brainstem (15)

This may include guidance on injection site rotation, storage, timing, disposal of needles, and what to do if a dose is missed

Developments in these areas aim not only to reduce symptoms, as current treatment options do, but also to restore thyroid function

This swelling can manifest in localized pain or tenderness, potentially indicating inflammation or other systemic responses to the medication