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By mimicking the hormone Glucagon-like-peptide-1 (GLP-1), this class of drugs slows stomach emptying, reduces appetite, and boosts insulin release (thus regulating blood sugar levels) both in the short-term and over time
An increase in MAPK6 expression, accompanying the rise in ROS levels and antioxidant enzyme expression, was also observed in previous work, although it occurred during the final storage period of blueberries exposed to UV-C radiation (Piechowiak et al., 2024)
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Increased cAMP stimulates several downstream effects, including cell membrane depolarization and an increase in cytosolic Ca 2+ concentration, that ultimately lead to secretion of insulin granules from beta cells (7)
