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As the primary outcome, the researchers evaluated the percentage change in body weight and the change in the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain score (in which higher scores reflect worse outcomes) from baseline to week 68

Snapshot Proponents Effective for L-carnitine deficiency Supports mitochondrial health and energy function Allegedly supports liver and brain health May improve PCOS in women and semen quality and fertility in men Skeptics Many popular uses are not supported by evidence May contribute to heart disease by metabolizing TMAO Can cause nausea or stomach upset Long-term use may cause oxidative stress in the liver and blood Affects thyroid function Health Benefits of Carnitine Effective for: L-Carnitine Deficiency (Genetic) Oral and intravenous L-carnitine is effective for the treatment of primary and secondary L-carnitine deficiency due to inborn errors of metabolism (genetic)

GLP-1 receptor agonists in the treatment of type 2 diabetes state-of-the-art