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These meds have been around since 2015, and have a good safety record

Chesney, J

Pharmaceutical GLP1 patches under development: aim to deliver a real GLP1 receptor agonist (such as exendin4 or semaglutide) using microneedle or advanced transdermal technologies, but these remain in preclinical or very early development stages and are not available as approved products

The primary endpoints are alteration of transcriptomic profile of tongue tissue as changes in expression level from baseline to follow-up after 16 weeks of treatment, measured by RNA sequencing, and change in taste sensitivity as detected by chemical gustometry