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Tonazzi A, Giangregorio N, Console L, Palmieri F, Indiveri C The mitochondrial carnitine acyl-carnitine carrier (SLC25A20): Molecular mechanisms of transport, role in redox sensing and interaction with drugs
The medication's effect on slowing gastric emptying means food remains in the stomach longer, potentially causing discomfort when lying down, particularly if meals are consumed close to bedtime
A high activity was encountered, Ki = 5.1 nM, to be compared with 23 (HA08) with a Ki of 3.3 nM, the latter comprising a 13-membered macrocyclic system