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Description

It can also help improve bone density, which can help stave off osteoporosis

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By competitively binding to p53, FOXO4-DRI displaces endogenous FOXO4, causing p53 nuclear exclusion and translocation to mitochondria where it triggers the intrinsic apoptotic pathway through caspase-3/7 activation

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The expression of genes involved in gluconeogenesis, glycogenolysis, lipid synthesis and transport, and catabolism were altered in untreated Hz animals and the expression of most of them was normalized by IGF-1 therapy

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