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Lustig R, Peterkova V, Skorodok J, De Schepper J, Velasquez-Mieyer P, Hollander A, Anderson J, Darby C, Tavorath R, Tran L: A global, randomized, double-blind, placebo-controlled trial of octreotide-LAR for the treatment of pediatric hypothalamic obesity
However, the report did not clarify how many participants fully discontinued treatment versus those who simply reduced their dosage while continuing therapy
Injectable GLP-1 receptor agonists such as semaglutide, liraglutide and exenatide have transformed care, but the shift toward oral alternatives points to a wider opportunity: creating solid oral dosage forms that improve patient experience without compromising performance
FDA-approved Rybelsus (the oral semaglutide tablet) and the Wegovy Pill required years of development and a specialized absorption-enhancing technology called SNAC to overcome this challenge
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