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The distinction affects metabolic rate, physical function, appearance, and long-term weight maintenance probability

Patients who have been on Wegovy or Zepbound through the program would face three options: Pay out of pocket at retail prices (currently $1,000-$1,300 per month) Discontinue the medication , which research suggests leads to significant weight regain Transition to an alternative covered treatment , such as bariatric surgery or other covered medications The STEP 1 extension study showed that patients who discontinued semaglutide regained approximately two-thirds of their lost weight within one year

Marine Drugs, 12 (1), 128152

As we head into the next 510 years of obesity and diabetes research, a priority will be to understand the molecular traits of beta cell functional recovery so as to harness these pathways for type 2 diabetes intervention