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One case report documented a patient who developed gastroparesis after rapid escalation from low-dose to therapeutic-dose semaglutide within weeks rather than following the standard monthly titration

doi: 10.1016/j.ecoenv.2021.112947 150 YuanATStillmanMJ

La Puma says semaglutide injection site reactions can cause the following serious side effects: Blistering hives or skin ulcers Infections (pus, warmth, or fever) Allergic reactions causing widespread rash These come about as either hypersensitivity reactions or from direct mast cell activation, leading to the release of histamine and other mediators, Dr