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Clinical Experience with Incretins as Initial Therapy In newly diagnosed patients requiring more than metformin to get to their individualized A1C goal, the choice for incretin therapy depends on several factors, including baseline A1C, body mass index, and comorbidities
The ultimate winner in this space will be a GLP-1 agonist that delivers sustained clinical benefits with an excellent long-term safety profile and minimal adverse effects
An initial 4-8 week assessment period allows evaluation of individual response and tolerance before committing to extended therapy
While weight loss may affect lung mechanics, evidence of inflammatory changes has been revealed that could explain this relationship
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