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Notably, the PNA model mimics a lean phenotype with subtle metabolic alterations and may phenocopy the human phenotype B of PCOS 45 , characterized by hyperandrogenism and oligo-anovulation, with cycle irregularities
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The trial showed that liraglutide, as an adjunct to diet and exercise, was associated with reduced body weight (mean weight loss was 8%) and improved metabolic control
Beyond the linkers connecting FcR domain and the functional domain fusions, only a single mutation in the IgG and a single mutation in FcR are required to generate the complex
