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But here is the part that surprises most people: the differences between approved sites are small enough that the FDA considers them clinically equivalent

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Effects of exendine-4 on the differentiation of insulin producing cells from rat adipose-derived mesenchymal stem cells

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This ERK-without-Akt profile supports cellular proliferation and survival while maintaining cells in a proliferative rather than differentiated state contrasting sharply with IGF-1s PI3K/Akt/mTOR-dominant signalling, which drives protein synthesis and differentiation

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doi:10.1055/s-0035-1569330 40

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