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oasis 1 trial oral semaglutide 50 mg obesity nejm 2023 Semaglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, has well-established weight-loss benefits. Cagrilintide, a long-acting analogue of the satiety hormone amylin, has shown promise for weight loss in early trials. The potential Once-Weekly Semaglutide in Adults with

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