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"Antioxidant gene activation as a mechanism of oxidative stress mitigation" for its role in antioxidant gene upregulation), its core innovation lies in using lncRNA/plasmid delivery to modulate non-coding RNA networksa broader gene regulation strategy that extends beyond targeted antioxidant gene activation [103].Both in vivo experiments and oxygen-glucose deprivation/reoxygenation (OGD/R) cellular assays confirm the systems efficacy and biosafety

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