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Sorafenib, an FDA-approved multi-target kinase inhibitor, is the first-line systemic therapy for advanced HCC

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The rationale for triple agonism is based on preclinical research demonstrating that glucagon receptor activation contributes to energy expenditure and lipid metabolism through distinct mechanisms from those engaged by GLP-1R and GIPR agonism

A normal reaction may include: Mild redness Small raised bump Mild itching Slight tenderness Localized swelling Flow Wellness typically expects these symptoms to improve within a few days