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The main cons are that Retatrutide is not yet approved for clinical use, gastrointestinal side effects are common during the first 8 to 12 weeks, a new safety signal called dysesthesia emerged in Phase 3, long-term data beyond 68 weeks is still limited, and weight tends to return after discontinuing treatment

Medications such as semaglutide and liraglutide have been noted to provide benefits, including improved glycemic control, weight loss, and a reduction in cardiovascular risk

Gastrointestinal disorders: Metformin may cause gastrointestinal disorders (nausea, vomiting, diarrhea)[14]

Epitalon Spray is a high-quality anti-aging supplement formulated for direct human consumption