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Although semaglutide is currently the only GLP-1 RA with a specific indication for CKD progression, other agents in the class such as liraglutide and dulaglutide remain clinically relevant in the management of T2D and may offer renal benefits
According to NICE guidance, SGLT2 inhibitors are generally prioritised for patients with established cardiovascular disease, while GLP-1 receptor agonists like semaglutide are recommended based on glycaemic control and weight management criteria
People with obesity may have higher healthcare costs for a variety of reasons, including the direct cost of treating obesity as well as the cost of obesity-treating related conditions such as cholesterol, hypertension, and elevated blood sugar
This is most common in weeks 4 to 20 and usually resolves as weight loss stabilizes
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