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This includes hot baths, saunas, tight underwear, and prolonged sitting
Data extraction focused on the study design, population characteristics, IF protocols, and reported outcomes
Glucuronidation (50-60%) - SAFE Primary detoxification pathway in adults Makes acetaminophen water-soluble for excretion INCREASES during pregnancy but cannot compensate for other pathway changes Severely underdeveloped in fetuses/newborns 2
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