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doi:10.1016/s0006-2952(98)00094-x 54
Semaglutide is broken down in the liver as part of its metabolism, and Xanax is also metabolized by liver enzymes
The added GCGR component is mechanistically significant: glucagon receptor engagement increases hepatic lipid oxidation and energy expenditure, a pharmacology distinct from incretin-only compounds
Yes but with nuance
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