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The rapid mobilization of cholesterol from adipose stores saturates bile
That includes the 1 in 3 Americans who are considered overweight, with a body mass index (BMI) between 25 and 29below the obesity threshold of 30
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Although data from early phase trials suggest that retatrutide is well tolerated with a similar adverse event profile to GLP-1 RAs, additional research assessing long-term safety and efficacy of retatrutide in people living with obesity and/or T2D (including cardiovascular outcomes) is awaited over the next five years
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