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In db/db mice and advanced glycation end-products (AGEs)-induced HK-2 cells, hyperactivation of the ERK signaling pathway contributes to the impairment of mitophagy flux via regulating TFEB in DKD (117)
no reliance should therefore be placed on them
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This careful process prevents any tiny glass shards from causing an injury and ensures the B12 solution remains sterile and ready for use
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