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Most people feel a lift after a B12 shot, but a minority feel briefly worse
For instance, one study noted that individuals who regularly took vitamin B12 supplements gained between 2.5 to 17 fewer pounds (1.2 to 7.7 kg) over a decade than those who didn't supplement
This is especially true for individuals who live in areas with limited sunlight exposure or have conditions that affect their ability to absorb vitamin D from food
This reduced activity, combined with a potentially slower metabolism that can occur with persistent nutrient deficiencies, could indirectly contribute to weight gain over time
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