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For instance, estrogen can increase the expression of beta-carotene transporter proteins in the liver, leading to higher plasma concentrations of beta-carotene in women ( 4 Beta-carotene and retinoid: the peripheral metabolism of thyroid hormones Carotenoids are lipophilic antioxidants copiously present as colored pigments in vegetables and fruits
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Novo Nordisk filed an NDA with the FDA on 18 December 2025 for CagriSema, the fixed-dose cagrilintide/semaglutide combination, but that submission covers the combination product and is still under review it is not an approval of cagrilintide on its own
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