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la segunda, los materiales para construir y la tercera, la recuperacin
Peroxisome proliferator-activated receptor coactivator 1 (PGC-1), a nuclear transcription coactivator, plays several roles in energy metabolism, including involvement in adaptive thermogenesis, mitochondrial biogenesis, hepatic gluconeogenesis, and -oxidation of fatty acids 19,20,21,22
2 Weight loss pharmacotherapies 2.1 GLP-1R and GIPR agonism reduce body weight in patients with obesity Early GLP-1R agonists were approved to treat T2D (13, 15, 16), but the potential weight lowering efficacy for this class of molecules first seen in rodents was not confirmed in humans until clinical trials with the first long-acting GLP-1 analogue, liraglutide (12)
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