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While no human cases have been directly attributed to semaglutide, patients with a personal or family history of MTC or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) should not use this medication

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Notably, RT-qPCR analysis showed a sharp increase in OCT4 mRNA expression, a marker of pluripotent stem cells and essential for TIC self-renewal [33], in the colonies formed in 3D gels relative to 2D culture conditions (Fig

, 217 , 2291-2298, doi: Galadari, S., Rahman, A., Pallichankandy, S., and Thayyullathil, F