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Safety Assessment Acute toxicity A single subcutaneous injection of AOD 9604 (50 mg/kg) did not cause death or obvious toxic reactions in mice
In between episodes of sickling, people with SCD are normally well
The practice profit comes from the spread between acquisition cost and payer reimbursement
This means a single 10mg vial can theoretically cover the first 12 to 13 weeks of a standard escalation protocol, using roughly 7mg through that period
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