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For detailed analysis, see our complete comparison of semaglutide versus tirzepatide
Sancho-Vaello E, Gil-Carton D, Francois P, Bonetti EJ, Kreir M, Pothula KR
Safety guides recommendations
Common physical changes patients describe after GLP-1-supported weight loss include: Looser skin around the abdomen, flanks, and lower back Sagging or bat wing tissue along the upper arms Thigh skin that appears crepey or hangs when sitting or standing Decreased fullness in the breasts or buttocks Less volume in the face, particularly the cheeks and under the eyes These changes can feel surprising
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